There are many people who are disabled and unable to leave the house most of the time, who could work were it not for this restriction.
Many people who want to try out a business idea but without taking the big risk and investing in dedicated premises.
Remember The Body Shop started fro Anita Roddick's kitchen table?
Many mothers who are at home, or carers whether full or part time, who could support themselves more rather then being dependent on benefits.
In this age of purpose built mixed live/work units it is time to lift the restrictions and encourage enterprise. It encourages healthy sustainable communities.